Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224003 | 1.00 | DPP4 (0.33) | DPP4DPP7SCN9ASLC18A3ALDH1A1 | |
| SCHEMBL2221226 | 1.00 | DPP4 (0.33) | DPP4DPP7SCN9ASLC18A3ALDH1A1 | |
| SCHEMBL29089569 | 1.00 | DPP4 (0.33) | DPP4DPP7SCN9ASLC18A3ALDH1A1 | |
| SCHEMBL2221215 | 1.00 | DPP4 (0.33) | DPP4DPP7SCN9ASLC18A3ALDH1A1 | |
| SCHEMBL2223995 | 1.00 | DPP4 (0.33) | DPP4DPP7SCN9ASLC18A3ALDH1A1 | |
| SCHEMBL288363 | 1.00 | DPP4 (0.33) | DPP4DPP7SCN9ASLC18A3ALDH1A1 | |
| SCHEMBL1964520 | 0.85 | L3MBTL3 (0.31) | ALDH1A1 | |
| SCHEMBL22467822 | 0.83 | SCN9A (0.32) | DPP4DPP7SCN9ASLC18A3ALDH1A1 | |
| SCHEMBL20973259 | 0.83 | SCN9A (0.32) | DPP4DPP7SCN9ASLC18A3ALDH1A1 | |
| SCHEMBL17801583 | 0.83 | SCN9A (0.32) | DPP4DPP7SCN9ASLC18A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157299-B | Tricyclic heterocyclic derivative, composition and application thereof | 北京丹擎医药科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117157299-A | Tricyclic heterocyclic derivative, composition and application thereof | 北京丹擎医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |
| WO-2011036576-A1 | GPR 119 MODULATORS | PFIZER INC. (US) | 2011-03-31 | — | — | WO | disclosed |