Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 9/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12422263 | 0.88 | GABRG2 (0.38) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL1550722 | 0.82 | GABRG2 (0.37) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL599783 | 0.81 | NR1H2 (0.40) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL29954668 | 0.77 | NR1H2 (0.40) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL29955454 | 0.77 | NR1H2 (0.39) | GABRG2GABRB3GABRA5GABRA1NR1H2 | |
| SCHEMBL2878161 | 0.77 | NR1H2 (0.40) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL2930214 | 0.77 | NR1H2 (0.39) | GABRG2GABRB3GABRA5GABRA1NR1H2 | |
| SCHEMBL2873485 | 0.76 | NR1H2 (0.40) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL17690271 | 0.75 | ESR2 (0.40) | GABRG2GABRB3GABRA5HTR6NR1H2 | |
| SCHEMBL2926879 | 0.75 | NR1H2 (0.40) | GABRG2GABRB3GABRA5NR1H2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828378-B2 | Kinase inhibitors and methods of use | INTELLIKINE LLC (US) | 2017-11-28 | — | — | US | disclosed |