Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | UGCG | Q16739 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | MTOR | P42345 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | GMNN | O75496 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12091630 | 1.00 | MEN1 (0.69) | MEN1KMT2AMAPTUGCGTP53 | |
| SCHEMBL16938510 | 1.00 | MEN1 (0.69) | MEN1KMT2AMAPTUGCGTP53 | |
| SCHEMBL12091628 | 1.00 | MEN1 (0.69) | MEN1KMT2AMAPTUGCGTP53 | |
| SCHEMBL5553004 | 0.91 | MEN1 (0.69) | MEN1KMT2AMAPTUGCGTP53 | |
| SCHEMBL19354949 | 0.89 | UGCG (0.55) | MEN1KMT2AMAPTUGCGTP53 | |
| SCHEMBL12091640 | 0.88 | UGCG (0.67) | MEN1KMT2AMAPTUGCGTP53 | |
| SCHEMBL13417389 | 0.88 | UGCG (0.67) | MEN1KMT2AMAPTUGCGTP53 | |
| SCHEMBL13569487 | 0.88 | UGCG (0.67) | MEN1KMT2AMAPTUGCGTP53 | |
| SCHEMBL7096768 | 0.86 | KMT2A (0.61) | MEN1KMT2AMAPTUGCGTP53 | |
| SCHEMBL6548257 | 0.85 | KMT2A (0.69) | MEN1KMT2AMAPTUGCGTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828349-B2 | 1-aryl-1-hydroxy-2,3-diamino-propyl amines, 1-heteroaryl-1-hydroxy-2,3-diamino-propyl amines and related compounds having analgesic and/or immuno stimulant activity | EXONHIT THERAPEUTICS SA (FR) | 2017-11-28 | — | — | US | disclosed |