Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | UGCG | Q16739 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | MTOR | P42345 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10209787 | 0.90 | UGCG (0.59) | KMT2AMEN1UGCGMAPTTP53 | |
| SCHEMBL19645362 | 0.86 | MEN1 (0.69) | KMT2AMEN1UGCGMAPTTP53 | |
| SCHEMBL12091628 | 0.86 | MEN1 (0.69) | KMT2AMEN1UGCGMAPTTP53 | |
| SCHEMBL16938510 | 0.86 | MEN1 (0.69) | KMT2AMEN1UGCGMAPTTP53 | |
| SCHEMBL12091630 | 0.86 | MEN1 (0.69) | KMT2AMEN1UGCGMAPTTP53 | |
| SCHEMBL13852060 | 0.85 | GPR88 (0.52) | KMT2AMEN1UGCGMAPTTP53 | |
| SCHEMBL28548614 | 0.85 | GPR88 (0.52) | KMT2AMEN1UGCGMAPTTP53 | |
| SCHEMBL5553004 | 0.84 | MEN1 (0.69) | KMT2AMEN1UGCGMAPTTP53 | |
| SCHEMBL495779 | 0.83 | KLK5 (0.55) | — | |
| SCHEMBL495781 | 0.83 | KLK5 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782992-B1 | Amino alcohol derivative and method for preparing the same | SEIKAGAKU KOGYO CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6335444-B1 | Amino alcohol derivative and method for preparing the same | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-01-01 | — | — | US | disclosed |
| US-5907039-A | Amino alcohol derivative and method for preparing the same | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1999-05-25 | — | — | US | disclosed |
| EP-0782992-A1 | Amino alcohol derivative and method for preparing the same | SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) (JP) | 1997-07-09 | — | — | EP | disclosed |