SCHEMBL1964539

SCHEMBL1964539

Nc1ccc(Oc2ccc(N)cc2Cl)c(Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.56
TSHR P16473 2/20 0.56
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
PDE7A Q13946 2/20 0.47
HPGD P15428 3/20 0.47
NR1I2 O75469 1/20 0.47
LMNA P02545 1/20 0.47
TTR P02766 1/20 0.47
PGR P06401 1/20 0.47
HSP90AA1 P07900 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
MAPT P10636 1/20 0.47
HSPA5 P11021 1/20 0.47
CBR1 P16152 1/20 0.47
TBXA2R P21731 1/20 0.47
SLC6A2 P23975 1/20 0.47
AGTR1 P30556 1/20 0.47
SLC6A3 Q01959 1/20 0.47
ALDH1A1 P00352 5/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9517127 0.95 CYP3A4 (0.52) CYP3A4TSHRCA1CA2PDE7A
SCHEMBL4962861 0.91 TTR (0.60) CYP3A4TSHRHPGDNR1I2LMNA
SCHEMBL632218 0.89 CYP3A4 (0.46) CYP3A4TSHRCA1CA2PDE7A
Hydrochloric Acid SCHEMBL11339581 0.89 TTR (0.58) CYP3A4TSHRHPGDNR1I2LMNA
SCHEMBL4318630 0.87 PDE7A (0.63) CYP3A4TSHRPDE7AHPGDMAPT
SCHEMBL5863479 0.86 MAPT (0.58) CYP3A4TSHRHPGDNR1I2LMNA
SCHEMBL22069563 0.86 TTR (0.50) CYP3A4TSHRPDE7AHPGDNR1I2
SCHEMBL22069692 0.84 RHEB (0.45) CYP3A4TSHRCA1CA2PDE7A
SCHEMBL1374919 0.83 CYP3A4 (0.58) CYP3A4TSHRPDE7ATTRMAPT
SCHEMBL30617019 0.83 CYP3A4 (0.58) CYP3A4TSHRPDE7ATTRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605222-B2 Gel permeation chromatography; isomeric bis(phthalimide) and bisphenol-a structural units SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-10-20 US claimed
US-20070043203-A1 Gel permeation chromatography; isomeric bis(phthalimide) and bisphenol-a structural units GENERAL ELECTRIC COMPANY (US) 2007-02-22 US claimed
EP-0722969-A1 Aromatic polyimides derived from aromatic dianhydrides and chlorinated aromatic diamines E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-07-24 EP claimed
US-5175240-A Using chlorinated aromatic diamine E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-29 US claimed
EP-0491306-A1 Aromatic polyimides derived from aromatic dianhydrides and chlorinated aromatic diamines E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-24 EP claimed
JP-4293936-A None JP disclosed
US-10765992-B2 Gas separation membrane module and method for gas separation UBE INDUSTRIES, LTD. (JP) 2020-09-08 US disclosed
US-10369515-B2 Gas separation membrane module and method for gas separation UBE INDUSTRIES, LTD. (JP) 2019-08-06 US disclosed
US-20190201839-A1 GAS SEPARATION MEMBRANE MODULE AND METHOD FOR GAS SEPARATION UBE CORPORATION (JP) 2019-07-04 US disclosed
US-20180221812-A1 GAS SEPARATION MEMBRANE MODULE AND METHOD FOR GAS SEPARATION UBE CORPORATION (JP) 2018-08-09 US disclosed
US-9718023-B2 Gas separation membrane module and gas separation method UBE INDUSTRIES, LTD. (JP) 2017-08-01 US disclosed
US-20150007729-A1 GAS SEPARATION MEMBRANE MODULE AND METHOD FOR GAS SEPARATION UBE INDUSTRIES (JP) 2015-01-08 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed
EP-0722969-A1 Aromatic polyimides derived from aromatic dianhydrides and chlorinated aromatic diamines E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-07-24 EP disclosed
EP-0722969-A1 Aromatic polyimides derived from aromatic dianhydrides and chlorinated aromatic diamines E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-07-24 EP disclosed
US-5175240-A Using chlorinated aromatic diamine E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-29 US disclosed
US-5175240-A Using chlorinated aromatic diamine E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-29 US disclosed
JP-H04293936-A AROMATIC POLYIMIDE DERIVED FROM AROMATIC ACID DIANHYDRIDE AND CHLORINATED AROMATIC DIAMINE E I DU PONT DE NEMOURS & CO 1992-10-19 JP disclosed
EP-0491306-A1 Aromatic polyimides derived from aromatic dianhydrides and chlorinated aromatic diamines E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-24 EP disclosed
EP-0491306-A1 Aromatic polyimides derived from aromatic dianhydrides and chlorinated aromatic diamines E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-24 EP disclosed