Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19882345 | 0.89 | MEN1 (0.33) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL21709546 | 0.87 | MEN1 (0.33) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL2994447 | 0.85 | MEN1 (0.40) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL9843774 | 0.80 | MEN1 (0.38) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL25036853 | 0.80 | MEN1 (0.31) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL20761558 | 0.80 | ALDH1A1 (0.32) | ALDH1A1 | |
| Water SCHEMBL9016316 | 0.78 | MEN1 (0.37) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL3002888 | 0.78 | MEN1 (0.37) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL22081726 | 0.77 | MEN1 (0.38) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL22081056 | 0.77 | MEN1 (0.38) | MEN1ALDH1A1LMNAALOX12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828346-B2 | N-myristoyl transferase inhibitors | UNIVERSITY OF DUNDEE (GB) | 2017-11-28 | — | — | US | disclosed |