Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | SSTR3 | P32745 | 9/20 | 0.54 |
| ▸ | SSTR5 | P35346 | 9/20 | 0.54 |
| ▸ | SSTR2 | P30874 | 8/20 | 0.54 |
| ▸ | SSTR4 | P31391 | 8/20 | 0.54 |
| ▸ | SSTR1 | P30872 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8831093 | 0.86 | POLB (0.60) | POLBLMNAKMT2ACYP3A4MAPT | |
| SCHEMBL17167535 | 0.84 | SSTR5 (0.48) | POLBSSTR3SSTR5SSTR2SSTR4 | |
| SCHEMBL23069352 | 0.84 | LMNA (0.66) | POLBSSTR3SSTR5SSTR2SSTR4 | |
| SCHEMBL18879529 | 0.84 | LMNA (0.66) | POLBSSTR3SSTR5SSTR2SSTR4 | |
| SCHEMBL23243950 | 0.84 | LMNA (0.66) | POLBSSTR3SSTR5SSTR2SSTR4 | |
| SCHEMBL29583989 | 0.84 | LMNA (0.66) | POLBSSTR3SSTR5SSTR2SSTR4 | |
| SCHEMBL29583980 | 0.83 | LMNA (0.67) | POLBLMNAKMT2ACYP3A4MAPT | |
| SCHEMBL19448820 | 0.83 | LMNA (0.67) | POLBLMNAKMT2ACYP3A4MAPT | |
| SCHEMBL17326724 | 0.81 | CYP3A4 (0.57) | POLBLMNAKMT2ACYP3A4MAPT | |
| SCHEMBL24130618 | 0.81 | CYP3A4 (0.57) | POLBLMNAKMT2ACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828341-B2 | Dendritic core compounds | VICTORIA LINK LIMITED (NZ) | 2017-11-28 | — | — | US | disclosed |