Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 18/20 | 1.00 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.73 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16056963 | 1.00 | NAAA (1.00) | NAAAASAH1CTSL | |
| SCHEMBL16056879 | 0.89 | NAAA (1.00) | NAAAASAH1 | |
| SCHEMBL19646562 | 0.89 | NAAA (1.00) | NAAAASAH1 | |
| SCHEMBL17577509 | 0.89 | NAAA (0.80) | NAAAASAH1CTSL | |
| SCHEMBL16056919 | 0.87 | NAAA (1.00) | NAAAASAH1 | |
| SCHEMBL16056932 | 0.86 | NAAA (0.76) | NAAAASAH1CTSL | |
| SCHEMBL17556898 | 0.86 | NAAA (0.76) | NAAAASAH1CTSL | |
| SCHEMBL4073930 | 0.86 | NAAA (0.85) | NAAAASAH1CTSL | |
| SCHEMBL4079431 | 0.86 | NAAA (0.85) | NAAAASAH1CTSL | |
| SCHEMBL4073924 | 0.86 | NAAA (0.85) | NAAAASAH1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828338-B2 | Carbamate derivatives of lactam based N-acylethanolamine acid amidase (NAAA) inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-11-28 | — | — | US | disclosed |