Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.34 |
| ▸ | GJB2 | P29033 | 1/20 | 0.34 |
| ▸ | GJA1 | P17302 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | AGXT | P21549 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404640 | 0.89 | KMT2A (0.36) | KMT2AMEN1L3MBTL1MMP1MMP3 | |
| SCHEMBL15481393 | 0.81 | L3MBTL1 (0.39) | KMT2AMEN1L3MBTL1GJB2GJA1 | |
| SCHEMBL16560364 | 0.81 | MEN1 (0.34) | KMT2AMEN1L3MBTL1GJB2GJA1 | |
| SCHEMBL15279226 | 0.80 | SLC5A2 (0.32) | KMT2AMEN1SLC5A2ALDH1A1 | |
| SCHEMBL10892517 | 0.79 | CA1 (0.50) | KMT2AMEN1L3MBTL1MMP1MMP3 | |
| SCHEMBL402934 | 0.78 | TACR1 (0.38) | KMT2AMEN1L3MBTL1KDM4EMAPT | |
| SCHEMBL9185521 | 0.77 | KMT2A (0.41) | KMT2AMEN1MMP1MMP3MMP9 | |
| SCHEMBL25845030 | 0.76 | CA1 (0.34) | KMT2AMEN1L3MBTL1MMP1MMP3 | |
| SCHEMBL15481395 | 0.76 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1 | |
| SCHEMBL1966486 | 0.75 | L3MBTL1 (0.53) | KMT2AMEN1L3MBTL1TACR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336144-B1 | ESTERIFIED ALPHA-GALACTOSYLCERAMIDE | RIKEN (JP) | 2015-01-21 | — | — | EP | disclosed |
| US-8580751-B2 | Esterified α-galactosylceramide | RIKEN (JP) | 2013-11-12 | — | — | US | disclosed |
| US-20110224158-A1 | ESTERIFIED ALPHA-GALACTOSYLCERAMIDE | RIKEN (JP) | 2011-09-15 | — | — | US | disclosed |
| EP-2336144-A1 | ESTERIFIED ALPHA-GALACTOSYLCERAMIDE | Riken (JP) | 2011-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224158-A1 | ESTERIFIED ALPHA-GALACTOSYLCERAMIDE | GBA1, UGCG, MAN2B1 | KMT2A 1251/4885MEN1 831/4885L3MBTL1 1058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.