Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713614 | 0.88 | ALDH1A1 (0.41) | ALDH1A1TSHRKDM4ECA2PTGS1 | |
| SCHEMBL673909 | 0.82 | — | — | |
| SCHEMBL28448859 | 0.78 | ALDH1A1 (0.44) | ALDH1A1TSHR | |
| SCHEMBL31028520 | 0.78 | ALDH1A1 (0.44) | ALDH1A1TSHR | |
| SCHEMBL18537219 | 0.77 | — | — | |
| SCHEMBL29236457 | 0.76 | ALDH1A1 (0.45) | ALDH1A1TSHRKDM4ECA2PTGS1 | |
| Acetic Acid SCHEMBL28864537 | 0.76 | FFAR3 (0.50) | ALDH1A1TSHR | |
| SCHEMBL2722612 | 0.75 | ALDH1A1 (0.47) | ALDH1A1TSHR | |
| SCHEMBL804118 | 0.75 | ALDH1A1 (0.47) | ALDH1A1TSHRKDM4ECA2PTGS1 | |
| SCHEMBL30366450 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9827249-B2 | Use of condensed benzo[B]thiazine derivatives as cytoprotectants | ARANDA PHARMA LTD (FI) | 2017-11-28 | — | — | US | disclosed |