Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2544217 | 1.00 | LMNA (0.46) | LMNAALDH1A1MTORTP53HTT | |
| SCHEMBL12230438 | 1.00 | LMNA (0.46) | LMNAALDH1A1MTORTP53HTT | |
| SCHEMBL12937911 | 1.00 | LMNA (0.46) | LMNAALDH1A1MTORTP53HTT | |
| SCHEMBL2544209 | 1.00 | LMNA (0.46) | LMNAALDH1A1MTORTP53HTT | |
| SCHEMBL12253298 | 0.84 | DNMT1 (0.33) | DNMT1 | |
| SCHEMBL2119424 | 0.84 | DNMT1 (0.49) | LMNADNMT1SMN1; SMN2 | |
| SCHEMBL2611588 | 0.84 | DNMT1 (0.49) | LMNADNMT1SMN1; SMN2 | |
| SCHEMBL6815174 | 0.84 | DNMT1 (0.33) | DNMT1 | |
| SCHEMBL22219920 | 0.84 | DNMT1 (0.49) | LMNADNMT1SMN1; SMN2 | |
| SCHEMBL2119433 | 0.84 | DNMT1 (0.49) | LMNADNMT1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828633-B1 | Modified nucleotides methods and kits | PIERCE BIOTECHNOLOGY, INC. (US) | 2017-11-28 | — | — | US | disclosed |