Agmatine

Agmatine

SCHEMBL19647

N=C(N)NCCCCN

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Agmatine SCHEMBL30819275 1.00
Agmatine SCHEMBL8579204 1.00 CYP1A2 (0.54)
Agmatine SCHEMBL5665180 1.00 CYP1A2 (0.54)
SCHEMBL433609 0.97 CYP1A2 (0.57)
Agmatine SCHEMBL20636599 0.97 SMN1; SMN2 (0.52)
Agmatine SCHEMBL23364117 0.97 CYP1A2 (0.52)
SCHEMBL5670730 0.97 CYP1A2 (0.57)
Agmatine SCHEMBL15974535 0.97 CYP1A2 (0.52)
SCHEMBL4109087 0.97 CYP1A2 (0.57)
Agmatine SCHEMBL7391507 0.97 SMN1; SMN2 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8702 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260148852-A1 ORGANIC MOLECULE EXPOSOMICS LINUS BIOTECHNOLOGY INC. (US) 2026-05-28 US claimed
EP-4223352-B1 DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS UROTRONIC INC (US) 2026-05-27 EP claimed
EP-4746880-A2 METHODS OF TREATING DILATED CARDIOMYOPATHY Regencor, Inc. (US) 2026-05-27 EP claimed
WO-2026107233-A2 COMPOSITIONS, SYSTEMS, AND METHODS FOR INCREASING NITRIC OXIDE IN A SUBJECT LifeActive, Inc. (US) 2026-05-21 WO claimed
US-20260137663-A1 ADMINISTRATION OF R-BETA-HYDROXYBUTYRATE SALT BLEND AND RELATED COMPOUNDS IN HUMANS AXCESS GLOBAL SCIENCES LLC (US) 2026-05-21 US claimed
WO-2026099467-A1 COMPOSITION FOR USE IN PROMOTING BRAIN DEVELOPMENT AND FUNCTIONING Société des Produits Nestlé S.A. (CH) 2026-05-15 WO claimed
CN-122036671-A Tetramethyl rhodamine-marked agmatine fluorescent probe and preparation method and application thereof 中国人民解放军陆军特色医学中心 2026-05-15 CN claimed
EP-4737581-A1 NOVEL SPERMIDINE AND AGMATINE PRODUCING BACILLUS STRAINS Evonik Operations GmbH (DE) 2026-05-06 EP claimed
EP-4731755-A2 COMPOSITIONS AND METHODS FOR REDUCING HOST CELL PROTEINS IN RECOMBINANT ADENO-ASSOCIATED VIRUS PREPARATIONS Ultragenyx Pharmaceutical Inc. (US) 2026-04-29 EP claimed
US-12612370-B2 Amino acid compositions THERMOLIFE INTERNATIONAL, LLC (US) 2026-04-28 US claimed
US-5077313-A PROCESS FOR INHIBITING PATHOLOGICAL COLLAGEN CROSS-LINKING IN DIABETES PATIENTS LUBEC GERT (AT) 1991-12-31 US claimed
EP-0443404-A1 Peptide fragments and analogs of thrombospondin W.R. Grace & Co.-Conn. (US) 1991-08-28 EP claimed
US-4957757-A Method of extending shelf life and enhancing keeping quality of fruits CORNELL RESEARCH FOUNDATION, INC. (US) 1990-09-18 US claimed
EP-0228034-A2 Arginine and agmatine derivatives for treating protozoal infections MERRELL DOW PHARMACEUTICALS INC. (US) 1987-07-08 EP claimed
US-4507321-A WOUND HEALING AGENTS THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1985-03-26 US claimed
US-4346078-A Novel anticoagulant agmatine derivatives and process for the preparation thereof RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1982-08-24 US claimed
US-4267102-A Bleomycin group antibiotics NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1981-05-12 US claimed
US-4138292-A ENZYMES OR MICROORGANISMS IN A SULFATED POLYSACCHARIDE GEL TANABE SEIYAKU CO., LTD. (JP) 1979-02-06 US claimed
US-4066506-A METHOD OF SEPARATING AND PURIFYING TWO ACTIVE FORMS OF UROKINASE USING AFFINITY CHROMATOGRAPHY THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF HEALTH, EDUCATION AND WELFARE (US) 1978-01-03 US claimed
US-3977942-A ARGININE, ORNITHINE, LYSINE, POLYAMINES MERCK & CO., INC. (US) 1976-08-31 US claimed