SCHEMBL433609

SCHEMBL433609

N=C(N)NCCCCCCCN

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
PAOX Q6QHF9 2/20 0.52
ALOX15 P16050 2/20 0.47
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA3 P07451 2/20 0.42
CA4 P22748 2/20 0.42
CA6 P23280 2/20 0.42
CA5A P35218 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CA5B Q9Y2D0 2/20 0.42
F13A1 P00488 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4109087 1.00 CYP1A2 (0.57) CYP1A2MEN1KMT2ASMN1; SMN2PAOX
SCHEMBL5670730 1.00 CYP1A2 (0.57) CYP1A2MEN1KMT2ASMN1; SMN2PAOX
SCHEMBL6698302 1.00 CYP1A2 (0.57) CYP1A2MEN1KMT2ASMN1; SMN2PAOX
SCHEMBL6698407 1.00 CYP1A2 (0.57) CYP1A2MEN1KMT2ASMN1; SMN2PAOX
Hydrochloric Acid SCHEMBL20543020 0.98 SMN1; SMN2 (0.55) CYP1A2MEN1KMT2ASMN1; SMN2PAOX
Agmatine SCHEMBL5665180 0.97 CYP1A2 (0.54) CYP1A2MEN1KMT2ASMN1; SMN2PAOX
Agmatine SCHEMBL30819275 0.97
Agmatine SCHEMBL19647 0.97
Agmatine SCHEMBL8579204 0.97 CYP1A2 (0.54) CYP1A2MEN1KMT2ASMN1; SMN2PAOX
Agmatine SCHEMBL23364117 0.95 CYP1A2 (0.52) CYP1A2MEN1KMT2ASMN1; SMN2PAOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240252664-A1 PRODUCT AND PROCESS FOR EMPLOYING GC7 (N1-GUANYL-1,7-DIAMINOHEPTANE) BASED ANTIGEN BINDING CONJUGATES IN CANCER THERAPY DE MAGALHAES NZOLA (US) 2024-08-01 US claimed
US-11865182-B2 Product and process for employing GC7 (N1-guanyl-1,7-diaminoheptane) based antigen binding conjugates in cancer therapy DE MAGALHAES NZOLA (US) 2024-01-09 US claimed
US-20200338205-A1 PRODUCT AND PROCESS FOR EMPLOYING GC7 (N1-GUANYL-1,7-DIAMINOHEPTANE) BASED ANTIGEN BINDING CONJUGATES IN CANCER THERAPY DE MAGALHAES NZOLA (US) 2020-10-29 US claimed
EP-1049444-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 2000-11-08 EP claimed
WO-1999037277-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 1999-07-29 WO claimed
US-12582625-B2 Methods for treating neuroblastoma USWM, LLC (US) 2026-03-24 US disclosed
US-20250186380-A1 METHODS FOR TREATING FAMILIAL ADENOMATOUS POLYPOSIS Cancer Prevention Pharmaceuticals (US) 2025-06-12 US disclosed
US-20250127742-A1 METHODS FOR TREATING NEUROBLASTOMA OAKTREE FUND ADMINISTRATION, LLC 2025-04-24 US disclosed
US-20240382589-A1 Synergistic Inhibition of eIF5A and Notch Signaling in Intermediate Tregs THE UNIVERSITY OF TOLEDO (US) 2024-11-21 US disclosed
US-20240307532-A1 Synergistic Inhibition of eIF5A and Notch Signaling in Intermediate Tregs THE UNIVERSITY OF TOLEDO (US) 2024-09-19 US disclosed
US-20240252664-A1 PRODUCT AND PROCESS FOR EMPLOYING GC7 (N1-GUANYL-1,7-DIAMINOHEPTANE) BASED ANTIGEN BINDING CONJUGATES IN CANCER THERAPY DE MAGALHAES NZOLA (US) 2024-08-01 US disclosed
US-20240165063-A1 METHODS FOR TREATING NEUROBLASTOMA NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-05-23 US disclosed
EP-1959010-A2 Apoptosis-specific eif-5A and polynucleotides encoding same Senesco Technologies, Inc. (US) 2008-08-20 EP disclosed
US-20070154457-A1 Use of eIF-5A to kill multiple myeloma cells SENESCO TECHNOLOGIES, INC. (US) 2007-07-05 US disclosed
US-20060287265-A1 Apoptosis-specific eIF-5A and polynucleotides encoding same SENESCO TECHNOLOGIES, INC. 2006-12-21 US disclosed
WO-2003106433-A1 DEOXYHYPUSINE-SYNTHASE INHIBITORS, PHARMACEUTICALS COMPRISING SAID INHIBITORS AND USES THEREOF VIAXXEL BIOTECH GMBH (DE) 2003-12-24 WO disclosed
US-20030233670-A1 Gene sequences and uses thereof in plants MONSANTO TECHNOLOGY LLC 2003-12-18 US disclosed
EP-1291414-A1 Ex vivo selection of T-cells with reduced alloreactivtiy (diminshed graft-versus-host effect and enhanced graft-verus-leukemia effect) and use therof in bone marrow transplantations Genethor GmbH (DE) 2003-03-12 EP disclosed
EP-1049444-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 2000-11-08 EP disclosed
WO-1999037277-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 1999-07-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240382589-A1 Synergistic Inhibition of eIF5A and Notch Signaling in Intermediate Tregs EIF2B5, EIF2B1, EIF5B CYP1A2 4155/4885MEN1 2038/4885KMT2A 1211/4885
US-20240307532-A1 Synergistic Inhibition of eIF5A and Notch Signaling in Intermediate Tregs EIF2B5, EIF5B, EIF2B1 CYP1A2 4224/4885MEN1 1686/4885KMT2A 1958/4885
US-12582625-B2 Methods for treating neuroblastoma ODC1, DDC, CD2 CYP1A2 1850/4885MEN1 380/4885KMT2A 493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.