SCHEMBL19647004

SCHEMBL19647004

NCCCc1cn([C@@H]2O[C@H](CO)CC2O)c(=O)nc1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 11/20 0.41
DNMT3B Q9UBC3 3/20 0.40
ALB P02768 1/20 0.38
ADRB1 P08588 1/20 0.37
FPR2 P25090 3/20 0.36
LMNA P02545 2/20 0.34
MTOR P42345 2/20 0.34
THRB P10828 1/20 0.34
MDM2 Q00987 1/20 0.34
NCOA1 Q15788 1/20 0.34
NCOA3 Q9Y6Q9 1/20 0.34
GMNN O75496 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
NFKB1 P19838 1/20 0.34
THPO P40225 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
BLM P54132 1/20 0.34
HBB P68871 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2579200 0.88 TK2 (0.42) DNMT1DNMT3BALBADRB1FPR2
SCHEMBL2589510 0.88 TK2 (0.42) DNMT1DNMT3BALBADRB1FPR2
SCHEMBL2579360 0.86 DNMT1 (0.42) DNMT1DNMT3BALBADRB1FPR2
SCHEMBL2579359 0.86 DNMT1 (0.42) DNMT1DNMT3BALBADRB1FPR2
SCHEMBL2580896 0.83 ALB (0.55) DNMT1DNMT3BALBADRB1LMNA
SCHEMBL2580898 0.83 ALB (0.55) DNMT1DNMT3BALBADRB1LMNA
SCHEMBL19657159 0.83 ALB (0.55) DNMT1DNMT3BALBADRB1LMNA
SCHEMBL5717526 0.83 ALB (0.55) DNMT1DNMT3BALBADRB1LMNA
SCHEMBL19647005 0.83 DNMT1 (0.41) DNMT1DNMT3BALBADRB1FPR2
SCHEMBL2583043 0.83 DNMT1 (0.42) DNMT1DNMT3BALBADRB1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9828633-B1 Modified nucleotides methods and kits PIERCE BIOTECHNOLOGY, INC. (US) 2017-11-28 US disclosed