Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | CLPP | Q16740 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15483785 | 1.00 | PDK1 (0.40) | PDK1MAPTHTTTDP1MAPK1 | |
| SCHEMBL15483722 | 1.00 | PDK1 (0.40) | PDK1MAPTHTTTDP1MAPK1 | |
| SCHEMBL888129 | 0.85 | PDK1 (0.38) | PDK1MAPTTDP1MAPK1L3MBTL1 | |
| SCHEMBL888146 | 0.83 | PDK1 (0.44) | PDK1MAPTHTTTDP1MAPK1 | |
| SCHEMBL2065622 | 0.83 | PDK1 (0.44) | PDK1MAPTHTTTDP1MAPK1 | |
| SCHEMBL10177990 | 0.83 | PDK1 (0.44) | PDK1MAPTHTTTDP1MAPK1 | |
| SCHEMBL1665434 | 0.80 | PDK1 (0.42) | PDK1MAPTHTTTDP1MAPK1 | |
| SCHEMBL10178329 | 0.80 | PDK1 (0.42) | PDK1MAPTHTTTDP1MAPK1 | |
| SCHEMBL890038 | 0.80 | PDK1 (0.42) | PDK1MAPTHTTTDP1MAPK1 | |
| SCHEMBL1514928 | 0.80 | PDK1 (0.42) | PDK1MAPTHTTTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307565-B1 | REVERSIBLE NUCLEOSIDES AND NUCLEOTIDES TERMINATORS AND THEIR USE IN DNA SEQUENCING | LASERGEN INC (US) | 2017-11-29 | — | — | EP | disclosed |