Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19450424 | 0.80 | TGM2 (0.42) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL21031688 | 0.75 | SMN1; SMN2 (0.41) | TRPV1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL13104357 | 0.72 | NPC1 (0.52) | TRPV1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL24004174 | 0.72 | KDM4E (0.54) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL20880915 | 0.71 | NPSR1 (0.35) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL23463556 | 0.71 | TRPV1 (0.39) | TRPV1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL22903134 | 0.70 | HDAC3 (0.49) | TRPV1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL22914719 | 0.69 | NPC1 (0.49) | TRPV1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL23343671 | 0.68 | MAPT (0.47) | TRPV1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL12233865 | 0.68 | MAPT (0.58) | TRPV1SMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |
| EP-3249707-A1 | ORGANIC COMPOUND AND LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DIODE DISPLAY DEVICE USING THE SAME | LG Display Co., Ltd. (KR) | 2017-11-29 | — | — | EP | disclosed |