Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 20/20 | 0.51 |
| ▸ | IKBKE | Q14164 | 10/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14981860 | 0.87 | TBK1 (0.61) | TBK1IKBKE | |
| SCHEMBL14976697 | 0.87 | TBK1 (0.60) | TBK1IKBKE | |
| SCHEMBL14977131 | 0.86 | TBK1 (0.61) | TBK1IKBKE | |
| SCHEMBL14977054 | 0.85 | TBK1 (0.68) | TBK1 | |
| SCHEMBL14976741 | 0.85 | TBK1 (0.61) | TBK1IKBKE | |
| SCHEMBL15555470 | 0.82 | TBK1 (0.57) | TBK1IKBKE | |
| SCHEMBL15555443 | 0.82 | TBK1 (0.51) | TBK1IKBKE | |
| SCHEMBL14976749 | 0.82 | TBK1 (0.50) | TBK1IKBKE | |
| SCHEMBL14977031 | 0.81 | TBK1 (0.62) | TBK1IKBKE | |
| SCHEMBL15555343 | 0.80 | TBK1 (0.49) | TBK1IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794602-B1 | 3-CYANARYL-1H-PYRAZOLO(2.3-B) PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2017-11-29 | — | — | EP | disclosed |