Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.47 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.47 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154178 | 0.89 | KDM4E (0.68) | KDM4ETP53CHRNA10CHRNA9MAPT | |
| SCHEMBL149656 | 0.87 | KDM4E (0.66) | KDM4ETP53CHRNA10CHRNA9MAPT | |
| SCHEMBL139427 | 0.87 | KDM4E (0.66) | KDM4ETP53CHRNA10CHRNA9MAPT | |
| SCHEMBL7402909 | 0.85 | KDM4E (0.68) | KDM4ETP53CHRNA10CHRNA9MAPT | |
| SCHEMBL2234557 | 0.81 | KDM4E (0.59) | KDM4ETP53CHRNA10CHRNA9MAPT | |
| SCHEMBL13098159 | 0.81 | KDM4E (0.59) | KDM4ETP53CHRNA10CHRNA9MAPT | |
| SCHEMBL2384959 | 0.80 | KDM4E (0.80) | KDM4ETP53CHRNA10CHRNA9PANK3 | |
| SCHEMBL18409049 | 0.79 | KDM4E (0.56) | KDM4ETP53CHRNA10CHRNA9MAPT | |
| SCHEMBL12071033 | 0.79 | KDM4E (0.56) | KDM4ETP53CHRNA10CHRNA9MAPT | |
| SCHEMBL12635874 | 0.79 | KDM4E (0.56) | KDM4ETP53CHRNA10CHRNA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2580289-B1 | BLACK DICHROIC DYE | BASF SE (DE) | 2017-11-29 | — | — | EP | disclosed |