Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.56 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL139427 | 0.98 | KDM4E (0.66) | KDM4ETP53CHRNA10CHRNA9ALDH1A1 | |
| SCHEMBL149656 | 0.98 | KDM4E (0.66) | KDM4ETP53CHRNA10CHRNA9ALDH1A1 | |
| SCHEMBL7402909 | 0.95 | KDM4E (0.68) | KDM4ETP53CHRNA10CHRNA9ALDH1A1 | |
| SCHEMBL2234557 | 0.92 | KDM4E (0.59) | KDM4ETP53CHRNA10CHRNA9ALDH1A1 | |
| SCHEMBL13098159 | 0.92 | KDM4E (0.59) | KDM4ETP53CHRNA10CHRNA9ALDH1A1 | |
| SCHEMBL2384959 | 0.91 | KDM4E (0.80) | KDM4ETP53CHRNA10CHRNA9ALDH1A1 | |
| SCHEMBL18409049 | 0.89 | KDM4E (0.56) | KDM4ETP53CHRNA10CHRNA9ALDH1A1 | |
| SCHEMBL12071033 | 0.89 | KDM4E (0.56) | KDM4ETP53CHRNA10CHRNA9ALDH1A1 | |
| SCHEMBL19648941 | 0.89 | KDM4E (0.56) | KDM4ETP53CHRNA10CHRNA9ALDH1A1 | |
| SCHEMBL12635874 | 0.89 | KDM4E (0.56) | KDM4ETP53CHRNA10CHRNA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12605450-B2 | C3-carbon linked glutarimide Degronimers for target protein degradation | C4 THERAPEUTICS, INC. (US) | 2026-04-21 | — | — | US | disclosed |
| EP-4717317-A2 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | C4 Therapeutics, Inc. (US) | 2026-04-01 | — | — | EP | disclosed |
| US-12570626-B2 | Degraders and degrons for targeted protein degradation | C4 THERAPEUTICS, INC. (US) | 2026-03-10 | — | — | US | disclosed |
| EP-3641762-B1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | C4 THERAPEUTICS INC (US) | 2026-02-18 | — | — | EP | disclosed |
| US-20260015338-A1 | TARGETED PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2026-01-15 | — | — | US | disclosed |
| US-20260015362-A1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2026-01-15 | — | — | US | disclosed |
| US-20250382285-A1 | BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS | C4 THERAPEUTICS, INC. (US) | 2025-12-18 | — | — | US | disclosed |
| US-20250368631-A1 | BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS | C4 THERAPEUTICS, INC. (US) | 2025-12-04 | — | — | US | disclosed |
| US-12454521-B2 | Targeted protein degradation | C4 THERAPEUTICS, INC. | 2025-10-28 | — | — | US | disclosed |
| US-12441740-B2 | N/O-linked degrons and degronimers for protein degradation | C4 THERAPEUTICS, INC. (US) | 2025-10-14 | — | — | US | disclosed |
| EP-0863144-A1 | IMIDAZOQUINAZOLINE DERIVATIVES | Kyowa Hakko Co., Ltd. (JP) | 1998-09-09 | — | — | EP | disclosed |
| EP-0639587-B1 | Diene polymers and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents | BRIDGESTONE FIRESTONE INC (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0543128-B1 | Diene polymers and copolymers terminated by reaction with aromatic nitriles | BRIDGESTONE FIRESTONE INC (US) | 1997-01-08 | — | — | EP | disclosed |
| EP-0543305-B1 | Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from fused-ring polynuclear aromatic compounds or aromatic nitrile compounds | BRIDGESTONE CORP (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0639587-A1 | Diene polymeres and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents | BRIDGESTONE/FIRESTONE, INC. (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5310798-A | Tire treads | BRIDGESTONE/FIRESTONE, INC. (US) | 1994-05-10 | — | — | US | disclosed |
| US-5254628-A | Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from aromatic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 1993-10-19 | — | — | US | disclosed |
| EP-0543305-A1 | Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from fused-ring polynuclear aromatic compounds or aromatic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 1993-05-26 | — | — | EP | disclosed |
| EP-0543128-A1 | Diene polymers and copolymers terminated by reaction with aromatic nitriles | BRIDGESTONE/FIRESTONE, INC. (US) | 1993-05-26 | — | — | EP | disclosed |
| US-5153271-A | Conjugated homo- or copolyenes, aromatic olefin copolymers endcapped by benzonitrile(or derivataives), for reduced hystersis in tire treads | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250368631-A1 | BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS | CRBN, STUB1, CUL1 | KDM4E 465/4885TP53 674/4885CHRNA10 1857/4885 |
| US-12605450-B2 | C3-carbon linked glutarimide Degronimers for target protein degradation | NEDD4, UBE3A, UBE3C | KDM4E 1603/4885TP53 603/4885CHRNA10 1135/4885 |
| US-12441740-B2 | N/O-linked degrons and degronimers for protein degradation | CRBN, CBL, STUB1 | KDM4E 1099/4885TP53 119/4885CHRNA10 2630/4885 |
| US-20260015338-A1 | TARGETED PROTEIN DEGRADATION | PSMC3, PSMA6, ADRM1 | KDM4E 1157/4885TP53 557/4885CHRNA10 4173/4885 |
| US-12570626-B2 | Degraders and degrons for targeted protein degradation | ADRM1, UCHL3, USP30 | KDM4E 2163/4885TP53 367/4885CHRNA10 3685/4885 |
| US-20260015362-A1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | CRBN, CBLC, CBL | KDM4E 1492/4885TP53 185/4885CHRNA10 1459/4885 |
| US-12454521-B2 | Targeted protein degradation | STUB1, MDM2, UBE3A | KDM4E 781/4885TP53 180/4885CHRNA10 4709/4885 |
| US-20250382285-A1 | BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS | CRBN, STUB1, CUL1 | KDM4E 465/4885TP53 674/4885CHRNA10 1857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.