Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 2/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19649059 | 0.82 | MEN1 (0.69) | RAB9AMEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL14393489 | 0.81 | RAB9A (0.47) | RAB9AMEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL12657103 | 0.80 | RAB9A (0.67) | RAB9AMEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL10104233 | 0.79 | RAB9A (0.46) | RAB9AMEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL19649001 | 0.78 | RAB9A (0.39) | RAB9AMEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL12657241 | 0.78 | RAB9A (0.47) | RAB9AMEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL19649186 | 0.75 | KDM4A (0.54) | RAB9AMEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL19649083 | 0.75 | MEN1 (0.50) | RAB9AMEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL13043411 | 0.74 | RAB9A (0.48) | RAB9AMEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL16070586 | 0.74 | KDM4A (0.47) | RAB9AMEN1NPC1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2677996-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'ORÉAL (FR) | 2017-11-29 | — | — | EP | disclosed |