Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ESRRG | P62508 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL52004 | 0.86 | ESR1 (0.50) | ESR1ESR2CYP3A4ALDH1A1ESRRG | |
| SCHEMBL8374002 | 0.81 | ESR1 (0.53) | ESR1ESR2CYP3A4ALDH1A1ESRRG | |
| SCHEMBL22193637 | 0.77 | ESR1 (0.67) | ESR1ESR2CYP3A4ALDH1A1ESRRG | |
| SCHEMBL8767918 | 0.77 | ESR1 (0.67) | ESR1ESR2CYP3A4ALDH1A1ESRRG | |
| SCHEMBL24585316 | 0.77 | ESR1 (0.57) | ESR1ESR2CYP3A4ALDH1A1ESRRG | |
| SCHEMBL8761434 | 0.75 | ESR2 (0.48) | ESR1ESR2CYP3A4ALDH1A1ESRRG | |
| SCHEMBL16609100 | 0.75 | ESR1 (0.47) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL8761103 | 0.74 | KDM4E (0.40) | ESR1ESR2CYP3A4ALDH1A1ESRRG | |
| SCHEMBL13184033 | 0.74 | ESR1 (0.40) | ESR1ESR2CYP3A4ALDH1A1ESRRG | |
| SCHEMBL8760897 | 0.73 | SLC6A2 (0.44) | ESR1ESR2CYP3A4ALDH1A1ESRRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3249471-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | Canon Kabushiki Kaisha (JP) | 2017-11-29 | — | — | EP | disclosed |