Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760077 | 0.88 | LTA4H (0.54) | HPGDLTA4HESR1CYP3A4ESR2 | |
| SCHEMBL24119613 | 0.85 | HPGD (0.55) | SLC6A2PTGS1MAPTHPGDPOLB | |
| SCHEMBL8760889 | 0.85 | LTA4H (0.57) | LTA4HESR1ESR2GAANR5A1 | |
| SCHEMBL52004 | 0.85 | ESR1 (0.50) | SLC6A2HPGDMEN1KMT2ASLC6A4 | |
| SCHEMBL8761434 | 0.84 | ESR2 (0.48) | SLC6A2MAPTHPGDMEN1KMT2A | |
| SCHEMBL3173896 | 0.83 | SLC6A2 (0.58) | SLC6A2PTGS1MAPTHPGDPOLB | |
| SCHEMBL8761103 | 0.83 | KDM4E (0.40) | SLC6A2HPGDMEN1KMT2ASLC6A4 | |
| SCHEMBL18773750 | 0.81 | NR5A1 (0.65) | MAPTLTA4HLMNATSHRHSD17B10 | |
| SCHEMBL8374002 | 0.80 | ESR1 (0.53) | SLC6A2HPGDMEN1KMT2ASLC6A4 | |
| SCHEMBL26302544 | 0.79 | SLC6A2 (0.33) | SLC6A2PTGS1HPGDSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497465-B1 | Record material | APPLETON PAPER INC (US) | 1997-06-04 | — | — | EP | disclosed |
| EP-0497465-A1 | Record material | APPLETON PAPERS INC. (US) | 1992-08-05 | — | — | EP | disclosed |