Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 17/20 | 0.66 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.66 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.60 |
| ▸ | MINK1 | Q8N4C8 | 3/20 | 0.60 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.56 |
| ▸ | MARK3 | P27448 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966833 | 0.88 | S1PR1 (0.59) | S1PR1S1PR3MAP4K4MINK1DYRK3 | |
| SCHEMBL1963144 | 0.86 | S1PR1 (0.81) | S1PR1S1PR3MAP4K4MINK1 | |
| SCHEMBL1969510 | 0.83 | S1PR1 (0.69) | S1PR1S1PR3MAP4K4MINK1 | |
| SCHEMBL2989163 | 0.82 | S1PR1 (0.60) | S1PR1S1PR3MAP4K4MINK1 | |
| SCHEMBL3741047 | 0.82 | S1PR1 (0.73) | S1PR1S1PR3MAP4K4MINK1DYRK3 | |
| SCHEMBL3057688 | 0.82 | S1PR1 (0.71) | S1PR1S1PR3MAP4K4MINK1 | |
| SCHEMBL2989389 | 0.81 | S1PR1 (0.84) | S1PR1S1PR3MAP4K4MINK1 | |
| SCHEMBL1965040 | 0.80 | S1PR1 (0.65) | S1PR1S1PR3MAP4K4MINK1DYRK3 | |
| SCHEMBL1966006 | 0.80 | S1PR1 (0.81) | S1PR1S1PR3MAP4K4MINK1PRKCD | |
| SCHEMBL2998264 | 0.80 | S1PR1 (0.62) | S1PR1S1PR3MAP4K4MINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509424-A1 | NOVEL OXADIAZOLE COMPOUNDS | Abbott Laboratories (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011071570-A1 | NOVEL OXADIAZOLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-16 | — | — | WO | disclosed |