Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LAP3 | P28838 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20734476 | 1.00 | SPHK1 (0.48) | SPHK1OPRM1CYP2D6LMNATP53 | |
| SCHEMBL19596576 | 0.98 | OPRM1 (0.48) | SPHK1OPRM1CYP2D6LMNATP53 | |
| SCHEMBL26025316 | 0.98 | OPRM1 (0.48) | SPHK1OPRM1CYP2D6LMNATP53 | |
| SCHEMBL14605594 | 0.98 | OPRM1 (0.48) | SPHK1OPRM1CYP2D6LMNATP53 | |
| Hydrochloric Acid SCHEMBL28452464 | 0.88 | DPP7 (0.42) | SPHK1OPRM1TP53LAP3CYP3A4 | |
| SCHEMBL28989906 | 0.79 | GRIK1 (0.47) | SPHK1TP53LAP3MAPTGRIK1 | |
| SCHEMBL28989897 | 0.79 | GRIK1 (0.47) | SPHK1TP53LAP3MAPTGRIK1 | |
| SCHEMBL28989949 | 0.79 | GRIK1 (0.47) | SPHK1TP53LAP3MAPTGRIK1 | |
| SCHEMBL28989917 | 0.79 | GRIK1 (0.47) | SPHK1TP53LAP3MAPTGRIK1 | |
| SCHEMBL24725791 | 0.79 | GSR (0.52) | CYP1A2CYP3A4GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566494-B1 | CXCR4 RECEPTOR COMPOUNDS | ACER THERAPEUTICS INC (US) | 2017-11-29 | — | — | EP | disclosed |