Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23095094 | 0.95 | DHODH (0.49) | DHODHCYP19A1TNFCYP11B1ALDH1A1 | |
| SCHEMBL19637976 | 0.95 | ALDH1A1 (0.51) | DHODHCYP19A1TNFCYP11B1ALDH1A1 | |
| SCHEMBL19637994 | 0.93 | TNF (0.52) | DHODHCYP19A1TNFCYP11B1ALDH1A1 | |
| SCHEMBL30296928 | 0.93 | TNF (0.52) | DHODHCYP19A1TNFCYP11B1ALDH1A1 | |
| SCHEMBL17918140 | 0.93 | TNF (0.52) | DHODHCYP19A1TNFCYP11B1ALDH1A1 | |
| SCHEMBL19528974 | 0.93 | TNF (0.52) | DHODHCYP19A1TNFCYP11B1ALDH1A1 | |
| SCHEMBL19397376 | 0.93 | TNF (0.52) | DHODHCYP19A1TNFCYP11B1ALDH1A1 | |
| SCHEMBL17917886 | 0.93 | TNF (0.52) | DHODHCYP19A1TNFCYP11B1ALDH1A1 | |
| SCHEMBL23095071 | 0.93 | ALDH1A1 (0.52) | DHODHCYP19A1TNFCYP11B1ALDH1A1 | |
| SCHEMBL29776775 | 0.92 | ALDH1A1 (0.53) | DHODHCYP19A1TNFCYP11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3248966-B1 | PYRIMIDINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES | HODOGAYA CHEMICAL CO LTD (JP) | 2022-12-21 | — | — | EP | disclosed |
| US-10566543-B2 | Pyrimidine derivative and organic electroluminescent devices | HODOGAYA CHEMICAL CO., LTD. (JP) | 2020-02-18 | — | — | US | disclosed |
| EP-3248966-A1 | PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT | Hodogaya Chemical Co., Ltd. (JP) | 2017-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10566543-B2 | Pyrimidine derivative and organic electroluminescent devices | TYMS, TYMP, DPYD | DHODH 20/4885CYP19A1 1706/4885TNF 2244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.