SCHEMBL19650672

SCHEMBL19650672

C[Si](O)(O)CCCOCCO

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
MAPK1 P28482 1/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
THRB P10828 1/20 0.46
HTT P42858 1/20 0.46
MAPT P10636 1/20 0.46
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15199452 0.86 TSHR (0.52) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL10608124 0.83 TSHR (0.54) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL2406752 0.79 TSHR (0.50) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL28948881 0.79 TSHR (0.50) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL12131523 0.77 TSHR (0.48) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL29309501 0.77 TSHR (0.48) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL16342106 0.77 TSHR (0.54) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL28396161 0.77 TSHR (0.48) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL29430863 0.76 TSHR (0.52) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL19039345 0.76 TSHR (0.46) TSHRMAPK1MEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170341976-A1 ONE-PIECE, TRANSPARENT ANTI-CONDENSATION SUBSTRATE SAINT-GOBAIN GLASS FRANCE (FR) 2017-11-30 US disclosed