Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750809 | 0.92 | TSHR (0.43) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL17716670 | 0.92 | TSHR (0.54) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL47736 | 0.92 | TSHR (0.59) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL10331160 | 0.91 | TSHR (0.46) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL63384 | 0.91 | TSHR (0.46) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL26921080 | 0.91 | TSHR (0.46) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL19039345 | 0.91 | TSHR (0.46) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL31348327 | 0.91 | TSHR (0.46) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL15293381 | 0.90 | TSHR (0.57) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL10025723 | 0.90 | TSHR (0.42) | TSHRMAPK1MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410433-B | Silicon-containing polyurethane resin, preparation method thereof and synthetic leather bass | 广州海豚新材料有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-114958269-B | Fluorine-silicon modified polyurea sealant with long pot life and preparation method thereof | 万华化学集团股份有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-116410433-A | Silicon-containing polyurethane resin, preparation method thereof and synthetic leather bass | 广州海豚新材料有限公司 | 2023-07-11 | — | — | CN | claimed |
| CN-116143994-A | Aqueous organosilicon modified polyurethane dispersoid, preparation method thereof, synthetic leather surface layer containing aqueous organosilicon modified polyurethane dispersoid and luggage leather | 广州海豚新材料有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-115141671-B | Alkyl modified silicone oil insulating lubricating grease | 深圳市润仕达润滑材料有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115141671-A | Alkyl modified silicone oil insulating lubricating grease | 深圳市润仕达润滑材料有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-114958269-A | Fluorine-silicon modified polyurea sealant with long service life and preparation method thereof | 万华化学集团股份有限公司 | 2022-08-30 | — | — | CN | claimed |
| EP-2610281-B1 | Method of manufacturing hydrophilic silicone prepolymer | PEGAVISION CORP (TW) | 2017-02-15 | — | — | EP | claimed |
| US-9056879-B2 | Method of manufacturing hydrophilic silicone prepolymer | PEGAVISION CORPORATION (TW) | 2015-06-16 | — | — | US | claimed |
| US-20130172592-A1 | METHOD OF MANUFACTURING HYDROPHILIC SILICONE PREPOLYMER | PEGAVISION CORPORATION (TW) | 2013-07-04 | — | — | US | claimed |
| EP-2610281-A1 | Method of manufacturing hydrophilic silicone prepolymer | Pegavision Corporation (TW) | 2013-07-03 | — | — | EP | claimed |
| US-12116468-B2 | Composite particles comprising a hydrophobic dye and an amphiphilic block copolymer and use thereof in optical applications | COLOURSMITH LABS INC. (CA) | 2024-10-15 | — | — | US | disclosed |
| US-12031033-B2 | Zwitterionic polysiloxane for biomedical devices | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2024-07-09 | — | — | US | disclosed |
| EP-4291601-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS | Alcon Inc. (CH) | 2023-12-20 | — | — | EP | disclosed |
| US-11839700-B2 | Bio-electrode composition, bio-electrode, and method for manufacturing a bio-electrode | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-12-12 | — | — | US | disclosed |
| US-20060063852-A1 | Silicone hydrogel contact lens | ASAHIKASEI AIME CO. LTD. (JP) | 2006-03-23 | — | — | US | disclosed |
| US-6867245-B2 | Long wearable soft contact lens | ASAHIKASEI AIME CO., LTD. (JP) | 2005-03-15 | — | — | US | disclosed |
| US-20040192872-A1 | Long-wearable soft contact lens | ASAHIKASEI AIME CO., LTD (JP) | 2004-09-30 | — | — | US | disclosed |
| EP-1243960-A1 | SOFT CONTACT LENS CAPABLE OF BEING WORN FOR A LONG PERIOD | ASAHIKASEI AIME CO., Ltd. (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-20020016383-A1 | Long wearable soft contact lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2002-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172592-A1 | METHOD OF MANUFACTURING HYDROPHILIC SILICONE PREPOLYMER | RNGTT, HIRA, RCSD1 | TSHR 2114/4885MAPK1 3975/4885MEN1 4084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.