Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 7/20 | 0.52 |
| ▸ | HTR3A | P46098 | 6/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.50 |
| ▸ | HTR3B | O95264 | 2/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.50 |
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1965181 | 1.00 | CHRNA7 (0.52) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL1963771 | 0.85 | CHRNA7 (0.54) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL1964249 | 0.85 | CHRNA7 (0.54) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL1963512 | 0.83 | CHRNA7 (0.55) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL1965726 | 0.83 | HTR3A (0.59) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL1964961 | 0.83 | HTR3A (0.59) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL1962888 | 0.83 | HTR3A (0.59) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL1965416 | 0.82 | HTR3A (0.58) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL1963950 | 0.81 | CHRNA7 (0.57) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL492356 | 0.81 | CHRNA7 (0.67) | CHRNA7HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336128-A1 | Benzoisothiazoles and preparation and uses thereof | Memory Pharmaceuticals Corporation (US) | 2011-06-22 | — | — | EP | disclosed |