Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4208796 | 0.81 | LMNA (0.54) | MAPTMAPK1CERT1ASAH1MEN1 | |
| SCHEMBL4210359 | 0.81 | LMNA (0.54) | MAPTMAPK1CERT1ASAH1MEN1 | |
| SCHEMBL4208878 | 0.81 | LMNA (0.54) | MAPTMAPK1CERT1ASAH1MEN1 | |
| SCHEMBL4222011 | 0.81 | LMNA (0.54) | MAPTMAPK1CERT1ASAH1MEN1 | |
| SCHEMBL964482 | 0.81 | LMNA (0.54) | MAPTMAPK1CERT1ASAH1MEN1 | |
| SCHEMBL4220945 | 0.81 | LMNA (0.54) | MAPTMAPK1CERT1ASAH1MEN1 | |
| SCHEMBL963663 | 0.81 | LMNA (0.54) | MAPTMAPK1CERT1ASAH1MEN1 | |
| SCHEMBL962819 | 0.81 | LMNA (0.54) | MAPTMAPK1CERT1ASAH1MEN1 | |
| SCHEMBL966243 | 0.81 | LMNA (0.54) | MAPTMAPK1CERT1ASAH1MEN1 | |
| SCHEMBL966479 | 0.81 | LMNA (0.54) | MAPTMAPK1CERT1ASAH1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348866-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | Vascular Biogenics Ltd. (IL) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010052718-A9 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2011-06-16 | — | — | WO | disclosed |
| WO-2010052718-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2010-05-14 | — | — | WO | disclosed |