Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 13/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.37 |
| ▸ | ATR | Q13535 | 6/20 | 0.32 |
| ▸ | ATRIP | Q8WXE1 | 5/20 | 0.32 |
| ▸ | RPTOR | Q8N122 | 5/20 | 0.31 |
| ▸ | MLST8 | Q9BVC4 | 5/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.31 |
| ▸ | RICTOR | Q6R327 | 3/20 | 0.31 |
| ▸ | MAPKAP1 | Q9BPZ7 | 3/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16457161 | 0.81 | MTOR (0.41) | MTORPIK3CAPIK3CDATRATRIP | |
| SCHEMBL336770 | 0.77 | PIK3CA (0.55) | MTORPIK3CAPIK3CDATRATRIP | |
| SCHEMBL799341 | 0.73 | PIK3CA (0.42) | MTORPIK3CAPIK3CDRPTORMLST8 | |
| SCHEMBL370729 | 0.68 | MTOR (0.37) | MTORPIK3CAPIK3CD | |
| SCHEMBL336264 | 0.63 | PIK3CA (0.51) | MTORPIK3CAPIK3CDATRATRIP | |
| SCHEMBL25279339 | 0.63 | MTOR (0.45) | MTORPIK3CAPIK3CDATR | |
| SCHEMBL1610889 | 0.63 | MTOR (0.45) | MTORPIK3CAPIK3CDATR | |
| SCHEMBL1610886 | 0.63 | MTOR (0.45) | MTORPIK3CAPIK3CDATR | |
| SCHEMBL336286 | 0.63 | MTOR (0.48) | MTORPIK3CAPIK3CDATRATRIP | |
| SCHEMBL366555 | 0.62 | PIK3CA (0.42) | MTORPIK3CAPIK3CDPIK3R1PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336132-A1 | MORPHOLINOPURINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2011-06-22 | — | — | EP | disclosed |