Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 18/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 8/20 | 0.41 |
| ▸ | RICTOR | Q6R327 | 8/20 | 0.41 |
| ▸ | RPTOR | Q8N122 | 8/20 | 0.41 |
| ▸ | MAPKAP1 | Q9BPZ7 | 8/20 | 0.41 |
| ▸ | MLST8 | Q9BVC4 | 8/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336770 | 0.88 | PIK3CA (0.55) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL1965408 | 0.81 | MTOR (0.37) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL799341 | 0.80 | PIK3CA (0.42) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL336264 | 0.74 | PIK3CA (0.51) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL336657 | 0.72 | PIK3CA (0.61) | MTORPIK3CAPIK3R1RPTORMLST8 | |
| SCHEMBL337225 | 0.72 | PIK3CA (0.49) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL336390 | 0.72 | PIK3CA (0.57) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL337219 | 0.71 | PIK3CA (0.48) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL336267 | 0.70 | PIK3CA (0.47) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL336774 | 0.70 | PIK3CA (0.49) | MTORPIK3CAPIK3R1RICTORRPTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336132-B1 | MORPHOLINOPURINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2014-01-01 | — | — | EP | disclosed |