SCHEMBL19655160

SCHEMBL19655160

CC1(C)c2ccccc2-c2ccc(-c3nc4ccccc4nc3-n3c4ccccc4c4ccc5c6ccccc6n(-c6ccccc6)c5c43)cc21

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GSR P00390 1/20 0.31
TERT O14746 1/20 0.31
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
ALDH1A1 P00352 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22199782 0.91 RXFP1 (0.32) GSRTERTMAPK1HTTALDH1A1
SCHEMBL19655180 0.90 HRH4 (0.34) KDM4EL3MBTL1ALDH1A1
SCHEMBL19655225 0.90 KDM4E (0.32) KDM4EATML3MBTL1
SCHEMBL21168912 0.90 KDM4E (0.30) KDM4EATML3MBTL1
SCHEMBL21168901 0.90
SCHEMBL22141632 0.89 KDM4E (0.33) KDM4EATML3MBTL1MAPK1ALDH1A1
SCHEMBL19507876 0.89 FLT3 (0.32) TERT
SCHEMBL21454965 0.88 KDM4E (0.34) KDM4EATML3MBTL1GSRTERT
SCHEMBL19655134 0.87 PDE10A (0.31)
SCHEMBL19653885 0.86 KDM4E (0.32) KDM4EATML3MBTL1GSRTERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO KDM4E 2543/4885ATM 3559/4885L3MBTL1 2020/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO KDM4E 2543/4885ATM 3559/4885L3MBTL1 2020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.