Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22888314 | 1.00 | RIPK1 (0.52) | RIPK1 | |
| SCHEMBL22887818 | 0.92 | RIPK1 (0.46) | RIPK1 | |
| SCHEMBL22888271 | 0.85 | RIPK1 (0.48) | RIPK1 | |
| SCHEMBL22888762 | 0.85 | RIPK1 (0.42) | RIPK1 | |
| SCHEMBL19659265 | 0.84 | RIPK1 (0.53) | RIPK1 | |
| SCHEMBL19658983 | 0.83 | RIPK1 (0.45) | RIPK1 | |
| SCHEMBL18365806 | 0.82 | RIPK1 (0.44) | RIPK1 | |
| SCHEMBL18366331 | 0.82 | RIPK1 (0.44) | RIPK1 | |
| SCHEMBL18367465 | 0.82 | RIPK1 (0.44) | RIPK1 | |
| SCHEMBL18366332 | 0.82 | RIPK1 (0.44) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017004500-A9 | BICYCLIC LACTAMS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | WO | disclosed |