⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18882818 | 1.00 | — | — | |
| SCHEMBL18863235 | 1.00 | — | — | |
| SCHEMBL18863268 | 0.83 | CXCR1 (0.36) | — | |
| SCHEMBL18882794 | 0.83 | CXCR1 (0.36) | — | |
| SCHEMBL20424700 | 0.78 | — | — | |
| SCHEMBL14100207 | 0.75 | CXCR1 (0.30) | — | |
| SCHEMBL23612475 | 0.74 | — | — | |
| SCHEMBL18863222 | 0.72 | — | — | |
| SCHEMBL27089458 | 0.72 | — | — | |
| SCHEMBL18882811 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383386-B1 | MODULATORS OF CHEMOKINE RECEPTORS | CHEMOCENTRYX INC (US) | 2024-02-14 | — | — | EP | disclosed |
| US-11820759-B2 | Modulators of chemokine receptors | CHEMOCENTRYX, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-20220009912-A1 | MODULATORS OF CHEMOKINE RECEPTORS | CHEMOCENTRYX, INC. | 2022-01-13 | — | — | US | disclosed |
| US-10988464-B2 | Modulators of chemokine receptors | CHEMOCENTRYX, INC. (US) | 2021-04-27 | — | — | US | disclosed |
| US-20200039969-A1 | MODULATORS OF CHEMOKINE RECEPTORS | CHEMOCENTRYX, INC. | 2020-02-06 | — | — | US | disclosed |
| US-10336736-B2 | Modulators of chemokine receptors | CHEMOCENTRYX, INC. (US) | 2019-07-02 | — | — | US | disclosed |
| US-20180141934-A1 | MODULATORS OF CHEMOKINE RECEPTORS | CHEMOCENTRYX, INC. | 2018-05-24 | — | — | US | disclosed |
| US-9834545-B2 | Modulators of chemokine receptors | CHEMOCENTRYX, INC. (US) | 2017-12-05 | — | — | US | disclosed |