⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23612475 | 0.82 | — | — | |
| SCHEMBL18863235 | 0.78 | — | — | |
| SCHEMBL19655976 | 0.78 | — | — | |
| SCHEMBL18882818 | 0.78 | — | — | |
| SCHEMBL3116433 | 0.76 | LMNA (0.45) | — | |
| SCHEMBL3116427 | 0.76 | LMNA (0.45) | — | |
| SCHEMBL3116438 | 0.76 | LMNA (0.45) | — | |
| SCHEMBL3116431 | 0.76 | LMNA (0.45) | — | |
| SCHEMBL28776392 | 0.76 | LMNA (0.45) | — | |
| SCHEMBL26005425 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573972-B1 | RORGAMMA MODULATORS AND USES THEREOF | GENFIT (FR) | 2026-01-14 | — | — | EP | disclosed |
| US-11077115-B2 | Rorgamma modulators and uses thereof | GENFIT (FR) | 2021-08-03 | — | — | US | disclosed |
| WO-2018138359-A1 | RORGAMMA MODULATORS AND USES THEREOF | GENFIT (FR) | 2018-08-02 | — | — | WO | disclosed |