SCHEMBL19656169

SCHEMBL19656169

Cc1ccc(/C=C/C(=O)Oc2cccc3cccc(OC(=O)/C=C/c4ccc(C)cc4)c23)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.51
LMNA P02545 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
MEN1 O00255 1/20 0.51
HTT P42858 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
MAPT P10636 4/20 0.47
ALDH1A1 P00352 1/20 0.45
CYP3A4 P08684 1/20 0.45
HPGD P15428 1/20 0.45
ABCG2 Q9UNQ0 1/20 0.43
FOS P01100 1/20 0.43
JUN P05412 1/20 0.43
TRPM8 Q7Z2W7 1/20 0.42
CYP1B1 Q16678 1/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29563724 1.00 KMT2A (0.51) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL29563914 0.87 KMT2A (0.52) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL19656162 0.87 KMT2A (0.52) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL19656163 0.86 KMT2A (0.66) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL17576048 0.82 LMNA (0.56) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL20024204 0.82 LMNA (0.56) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL19642860 0.79 KMT2A (0.57) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL19642861 0.79 KMT2A (0.57) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL29563470 0.78 KDM4E (0.51) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL19656167 0.78 KDM4E (0.51) KMT2ALMNAL3MBTL1MEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11370854-B2 Non-phthalate donor for polyolefin catalysts BRASKEM AMERICA, INC. (US) 2022-06-28 US disclosed
US-20200223958-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W.R. GRACE & CO.-CONN. (US) 2020-07-16 US disclosed
US-10662267-B2 Non-phthalate donor for polyolefin catalysts W.R. GRACE & CO. -CONN. (US) 2020-05-26 US disclosed
US-20190270831-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W. R. GRACE & CO. - CONN. 2019-09-05 US disclosed
WO-2017204811-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W.R. GRACE & CO. -CONN. (US) 2017-11-30 WO disclosed