SCHEMBL19656539

SCHEMBL19656539

CC1(C)c2ccccc2-c2ccc(Nc3cc(-c4ccccc4)cc4c3sc3ccccc34)cc21

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TNKS O95271 1/20 0.34
▸ TNKS2 Q9H2K2 1/20 0.34
▸ PDK2 Q15119 2/20 0.33
▸ PARP14 Q460N5 1/20 0.32
▸ MAP3K8 P41279 2/20 0.32
▸ ALOX5 P09917 1/20 0.32
▸ MMP2 P08253 4/20 0.31
▸ MMP9 P14780 4/20 0.31
▸ MMP13 P45452 4/20 0.31
▸ MMP8 P22894 2/20 0.31
▸ PTGIR P43119 1/20 0.31
▸ MAPT P10636 2/20 0.31
▸ RIPK2 O43353 1/20 0.30
▸ EGFR P00533 1/20 0.30
▸ KDR P35968 1/20 0.30
▸ TGFBR1 P36897 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16802018 0.85 PARP14 (0.43) PDK2PARP14ALOX5PTGIRMAPT
SCHEMBL30192444 0.85 PARP14 (0.43) PDK2PARP14ALOX5PTGIRMAPT
SCHEMBL23372975 0.82 MAPT (0.34) PDK2MAP3K8PTGIRMAPT
SCHEMBL22136342 0.82 ALOX5 (0.43) PDK2PARP14MAP3K8ALOX5
SCHEMBL22136344 0.81 PTGIR (0.34) PDK2MAP3K8PTGIRMAPTRIPK2
SCHEMBL24969722 0.81 PARP14 (0.35) TNKSTNKS2PARP14MAP3K8ALOX5
SCHEMBL19656537 0.81 — —
SCHEMBL15138615 0.81 PTGIR (0.44) PDK2PARP14ALOX5MMP13PTGIR
SCHEMBL23372498 0.81 MAP3K8 (0.32) PDK2MAP3K8ALOX5RIPK2EGFR
SCHEMBL15714096 0.80 PDK2 (0.38) PDK2ALOX5MMP13PTGIRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021020799-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2021-02-04 — — WO disclosed
US-20210028370-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREFOR DUK SAN NEOLUX CO., LTD. (KR) 2021-01-28 — — US disclosed
EP-3466926-B1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME AND ELECTRONIC DEVICE THEREFOR DUK SAN NEOLUX CO LTD (KR) 2020-10-07 — — EP disclosed
WO-2020159135-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREFOR 덕산네오룩스 주식회사 2020-08-06 — — WO disclosed
WO-2019190101-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREFOR 덕산네오룩스 주식회사 2019-10-03 — — WO disclosed
US-20190296244-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME AND ELECTRONIC DEVICE THEREFOR DUK SAN NEOLUX CO., LTD. (KR) 2019-09-26 — — US disclosed
WO-2019160335-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2019-08-22 — — WO disclosed
EP-3466926-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME AND ELECTRONIC DEVICE THEREFOR Duk San Neolux Co., Ltd. (KR) 2019-04-10 — — EP disclosed
WO-2017204557-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME AND ELECTRONIC DEVICE THEREFOR 덕산네오룩스 주식회사 2017-11-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210028370-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREFOR OR51E2, WEE1, SLC39A11 TNKS 4125/4885TNKS2 4235/4885PDK2 1749/4885
US-20190296244-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME AND ELECTRONIC DEVICE THEREFOR OR51E2, WEE2, WEE1 TNKS 4626/4885TNKS2 4472/4885PDK2 1626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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