Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19656737 | 0.84 | AHR (0.31) | AHRMTNR1AMEN1MAPTKMT2A | |
| SCHEMBL19644278 | 0.83 | TP53 (0.37) | MTNR1AMEN1ALDH1A1KMT2A | |
| SCHEMBL19643518 | 0.75 | MAPK1 (0.35) | MTNR1A | |
| SCHEMBL14637434 | 0.74 | PLK1 (0.39) | GFERMEN1KMT2A | |
| SCHEMBL22492369 | 0.71 | F12 (0.43) | MEN1KMT2A | |
| SCHEMBL19642831 | 0.71 | CYP2C19 (0.36) | HSD17B10MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL19642830 | 0.71 | CYP2C19 (0.36) | HSD17B10MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL19127980 | 0.70 | KMT2A (0.33) | MTNR1AALDH1A1KMT2A | |
| SCHEMBL21160635 | 0.70 | SIRT1 (0.34) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL19643018 | 0.70 | HSD17B10 (0.33) | HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205296-A1 | AMINOACYLINDAZOLE IMMUNOMODULATORS FOR TREATMENT OF AUTOIMMUNE DISEASES | THE ROCKEFELLER UNIVERSITY (US) | 2017-11-30 | — | — | WO | disclosed |