⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18164612 | 1.00 | — | — | |
| SCHEMBL4766963 | 0.92 | — | — | |
| SCHEMBL31181891 | 0.90 | LMNA (0.46) | — | |
| SCHEMBL6252233 | 0.89 | ACE2 (0.48) | — | |
| SCHEMBL15687625 | 0.89 | ACE2 (0.48) | — | |
| SCHEMBL31187956 | 0.89 | ACE2 (0.48) | — | |
| SCHEMBL6252229 | 0.89 | ACE2 (0.48) | — | |
| SCHEMBL16408961 | 0.89 | ACE2 (0.48) | — | |
| SCHEMBL10745637 | 0.89 | ACE2 (0.48) | — | |
| SCHEMBL28719389 | 0.89 | ACE2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621557-B | Composite material based on modified polyether-ether-ketone and preparation method thereof | 宁波中科甬建新材料科技有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-114621557-A | Composite material based on modified polyether-ether-ketone and preparation method thereof | 宁波中科甬建新材料科技有限公司 | 2022-06-14 | — | — | CN | claimed |
| US-4100228-A | Transparent impact styrene polymer structure | THE DOW CHEMICAL COMPANY (US) | 1978-07-11 | — | — | US | claimed |
| CN-114621557-B | Composite material based on modified polyether-ether-ketone and preparation method thereof | 宁波中科甬建新材料科技有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-117776923-A | Crocetin diester compound and application thereof in liver cancer cell resistance | 常州大学 | 2024-03-29 | — | — | CN | disclosed |
| US-11725000-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2023-08-15 | — | — | US | disclosed |
| CN-114621557-A | Composite material based on modified polyether-ether-ketone and preparation method thereof | 宁波中科甬建新材料科技有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-107200687-B | Process for producing ethyl 4-methyloctanoate | 信越化学工业株式会社 | 2020-12-11 | — | — | CN | disclosed |
| EP-3008056-B1 | NOVEL GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-12-09 | — | — | EP | disclosed |
| EP-3707139-A1 | XANTHINE DERIVATIVES AND USES THEREOF AS INHIBITORS OF BROMODOMAINS OF BET PROTEINS | Centre National de la Recherche Scientifique (FR) | 2020-09-16 | — | — | EP | disclosed |
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |
| US-20030013875-A1 | 3-azabicyclo[3.1.0]hexane derivatives useful in therapy | PFIZER, INC. (US) | 2003-01-16 | — | — | US | disclosed |
| US-20020072616-A1 | 3-azabicyclo[3.1.0]hexane derivatives useful in therapy | PFIZER INC. | 2002-06-13 | — | — | US | disclosed |
| CN-1331679-A | 3-azabicyclo [3.1.0] hexane derivatives as opiate receptors ligands | PFIZER LTD (US) | 2002-01-16 | — | — | CN | disclosed |
| US-6313312-B1 | OPIATE RECEPTOR BINDERS; ALLERGIC DERMATITIS, PRURITUS; IRRITABLE BOWEL SYNDROME, GASTROINTESTINAL AND SKIN DISORDERS; VETERINARY MEDICINE; ANTI-ITCHING | PFIZER INC | 2001-11-06 | — | — | US | disclosed |
| US-5710335-A | REACTING RESORCIN WITH PRIMARY AMINE THEN ALKYL HALIDE | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-01-20 | — | — | US | disclosed |
| US-4046819-A | Alkylation of alkyl, cycloalkyl and aralkyl halides | UOP INC. (US) | 1977-09-06 | — | — | US | disclosed |
| US-4006188-A | Cycloalkenones | ZOECON CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |
| US-4000174-A | NOVEL COMPOUNDS | ZOECON CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-3954832-A | 16-And 16,16-methyl and ethyl substituted PGA1 -type compounds | THE UPJOHN COMPANY (US) | 1976-05-04 | — | — | US | disclosed |