Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.65 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.65 |
| ▸ | PNP | P00491 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239700 | 1.00 | ADRB1 (0.65) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL31309689 | 1.00 | ADRB1 (0.65) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL9151040 | 1.00 | ADRB1 (0.65) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL9151046 | 1.00 | ADRB1 (0.65) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL3478274 | 1.00 | ADRB1 (0.65) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL5981725 | 1.00 | ADRB1 (0.65) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL5981729 | 1.00 | ADRB1 (0.65) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL21423038 | 1.00 | ADRB1 (0.65) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL21423040 | 1.00 | ADRB1 (0.65) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL9153207 | 0.89 | ADRB1 (0.52) | ADRB1DNMT1PNPLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201585-A1 | MODULATORS OF DUX4 FOR REGULATION OF MUSCLE FUNCTION | GENEA IP HOLDINGS PTY LTD (AU) | 2017-11-30 | — | — | WO | disclosed |