Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 20/20 | 0.72 |
| ▸ | BRD4 | O60885 | 4/20 | 0.59 |
| ▸ | EP300 | Q09472 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29704370 | 0.93 | CREBBP (0.68) | CREBBPBRD4EP300 | |
| SCHEMBL19644087 | 0.93 | CREBBP (0.68) | CREBBPBRD4EP300 | |
| SCHEMBL21024053 | 0.92 | CREBBP (0.67) | CREBBPBRD4EP300 | |
| SCHEMBL19657764 | 0.92 | CREBBP (0.84) | CREBBPBRD4EP300 | |
| SCHEMBL19657357 | 0.92 | CREBBP (0.67) | CREBBPBRD4EP300 | |
| SCHEMBL29704392 | 0.87 | CREBBP (0.84) | CREBBPBRD4EP300 | |
| SCHEMBL19644119 | 0.87 | CREBBP (0.84) | CREBBPBRD4EP300 | |
| SCHEMBL29704456 | 0.86 | CREBBP (0.80) | CREBBPBRD4EP300 | |
| SCHEMBL19644120 | 0.86 | CREBBP (0.80) | CREBBPBRD4EP300 | |
| SCHEMBL21024320 | 0.85 | CREBBP (0.79) | CREBBPBRD4EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205536-A2 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | WO | disclosed |