Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 20/20 | 0.84 |
| ▸ | BRD4 | O60885 | 3/20 | 0.68 |
| ▸ | EP300 | Q09472 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19644119 | 1.00 | CREBBP (0.84) | CREBBPBRD4EP300 | |
| SCHEMBL19644307 | 0.91 | CREBBP (1.00) | CREBBPBRD4EP300 | |
| SCHEMBL29704383 | 0.91 | CREBBP (1.00) | CREBBPBRD4EP300 | |
| SCHEMBL19657680 | 0.88 | CREBBP (0.83) | CREBBPBRD4EP300 | |
| SCHEMBL19644425 | 0.88 | CREBBP (0.75) | CREBBPBRD4EP300 | |
| SCHEMBL19657356 | 0.87 | CREBBP (0.72) | CREBBPBRD4EP300 | |
| SCHEMBL29704502 | 0.86 | CREBBP (0.84) | CREBBPBRD4EP300 | |
| SCHEMBL19657352 | 0.86 | CREBBP (0.85) | CREBBPBRD4EP300 | |
| SCHEMBL19643469 | 0.86 | CREBBP (0.84) | CREBBPBRD4EP300 | |
| SCHEMBL29704370 | 0.85 | CREBBP (0.68) | CREBBPBRD4EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028617-A | Heterocyclic inhibitors of CBP/EP300 and their use in the treatment of cancer | 基因泰克公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-109476641-B | Heterocyclic inhibitors of CBP/EP300 and their use in the treatment of cancer | 基因泰克公司 | 2022-07-05 | — | — | CN | disclosed |