Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 6/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.36 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17902845 | 0.81 | TMPRSS2 (0.52) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL14101113 | 0.75 | ESR1 (0.68) | ESR1ESR2MEN1KMT2AKDM4E | |
| Trifluoroacetic Acid SCHEMBL17894529 | 0.73 | NR1H2 (0.42) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL31742171 | 0.73 | DPP7 (0.50) | ESR1ESR2CCR2ABHD6 | |
| Hydrochloric Acid SCHEMBL31021974 | 0.73 | DPP7 (0.49) | ESR1ESR2CCR2ABHD6GPR142 | |
| SCHEMBL19639431 | 0.72 | NR1H2 (0.41) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL13838815 | 0.72 | ESR1 (0.47) | ESR1ESR2NR1H2CCR2ABHD6 | |
| SCHEMBL13718336 | 0.72 | ESR1 (0.52) | ESR1ESR2CCR2ABHD6GPR142 | |
| SCHEMBL17894504 | 0.72 | NR1H2 (0.47) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL13718183 | 0.71 | NR1H2 (0.63) | ESR1ESR2MAPTMAPK1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | THE UNIVERSITY OF BATH (GB) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | ZYX, MPO, CFB | ESR1 2663/4885ESR2 2644/4885MEN1 3309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.