Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 20/20 | 0.74 |
| ▸ | BRD4 | O60885 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19644417 | 0.85 | CREBBP (1.00) | CREBBP | |
| SCHEMBL29704459 | 0.85 | CREBBP (1.00) | CREBBP | |
| SCHEMBL19657782 | 0.85 | CREBBP (0.83) | CREBBP | |
| SCHEMBL19657896 | 0.77 | CREBBP (0.65) | CREBBPBRD4 | |
| SCHEMBL19644468 | 0.75 | CREBBP (0.70) | CREBBPBRD4 | |
| SCHEMBL29704401 | 0.75 | CREBBP (0.70) | CREBBPBRD4 | |
| SCHEMBL25094215 | 0.75 | CREBBP (0.77) | CREBBPBRD4 | |
| SCHEMBL19657688 | 0.74 | CREBBP (0.76) | CREBBPBRD4 | |
| SCHEMBL22822505 | 0.74 | CREBBP (0.76) | CREBBPBRD4 | |
| SCHEMBL19644127 | 0.74 | CREBBP (1.00) | CREBBPBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205536-A2 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | WO | disclosed |