Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.80 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.71 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | MAOA | P21397 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 1/20 | 0.66 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.65 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL30758563 | 0.98 | MEN1 (0.77) | MEN1KMT2ATP53PTPN1EPHX1 | |
| SCHEMBL5080945 | 0.92 | MEN1 (0.86) | MEN1KMT2ATP53PTPN1EPHX1 | |
| SCHEMBL21798720 | 0.90 | KMT2A (0.76) | MEN1KMT2ATP53RAB9ANPC1 | |
| SCHEMBL3679372 | 0.90 | KMT2A (0.76) | MEN1KMT2ATP53RAB9ANPC1 | |
| SCHEMBL126415 | 0.89 | PTPN1 (0.87) | MEN1KMT2APTPN1RAB9ANPC1 | |
| SCHEMBL18103163 | 0.87 | NPC1 (0.88) | MEN1KMT2APTPN1RAB9ANPC1 | |
| SCHEMBL14715824 | 0.87 | NPC1 (0.88) | MEN1KMT2APTPN1RAB9ANPC1 | |
| SCHEMBL16583981 | 0.86 | KMT2A (0.74) | MEN1KMT2ATP53KDM4EPOLB | |
| SCHEMBL27180026 | 0.86 | TP53 (1.00) | MEN1KMT2ATP53RAB9ANPC1 | |
| SCHEMBL16592202 | 0.86 | KMT2A (0.74) | MEN1KMT2ATP53KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446381-A1 | ANTHRANILIC ACID AMIDES AND PHARMACEUTICAL USE THEREOF | Novartis AG (CH) | 2004-08-18 | — | — | EP | claimed |
| WO-2003040101-A1 | ANTHRANILIC ACID AMIDES AND PHARMACEUTICAL USE THEREOF | NOVARTIS AG (CH) | 2003-05-15 | — | — | WO | claimed |
| CN-119874605-A | Benzoyl piperidinyl piperidine derivatives, preparation method and application thereof | 南通大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-118271233-A | Nilaparil manufacturing method | 特沙诺有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-114835641-B | Synthesis method of 3-benzyl-6-bromo-2-methoxyquinoline | 南京杰运医药科技有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-115057794-B | Method for removing methylation of cerium catalytic oxidation amide by visible light induction | 桂林理工大学 | 2023-11-17 | — | — | CN | disclosed |
| US-11629137-B2 | Methods of manufacturing of niraparib | TESARO, INC. (US) | 2023-04-18 | — | — | US | disclosed |
| EP-4157888-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | Cullgen (Shanghai), Inc. (CN) | 2023-04-05 | — | — | EP | disclosed |
| CN-110483582-B | Aza-carbene-palladium complex crystal, synthesis method thereof and application thereof in preparing amide compound | 陕西师范大学 | 2023-02-10 | — | — | CN | disclosed |
| CN-115304507-A | Synthesis method of N-substituted aryl formamide | 兰州石化职业技术大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-115057794-A | Novel method for removing methylation of cerium-induced catalytic oxidation amide by visible light | 桂林理工大学 | 2022-09-16 | — | — | CN | disclosed |
| EP-0596057-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| EP-0595995-B1 | ARYLAMIDOALKYL- AND ARYLAMINOALKYL-N-HYDROXYUREA COMPOUNDS AND -N-HYDROXYFORMAMIDE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1997-01-15 | — | — | EP | disclosed |
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |
| EP-0595995-A4 | ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1994-08-24 | — | — | EP | disclosed |
| EP-0595995-A1 | ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY. | ABBOTT LAB (US) | 1994-05-11 | — | — | EP | disclosed |
| EP-0596057-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-05-11 | — | — | EP | disclosed |
| WO-1993021183-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |
| US-5214204-A | Inhibitors of biosynthesis of leukotrienes | ABBOTT LABORATORIES (US) | 1993-05-25 | — | — | US | disclosed |
| WO-1993002037-A1 | ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1993-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11629137-B2 | Methods of manufacturing of niraparib | PARP2, PARP1, PARP3 | MEN1 2505/4885KMT2A 182/4885TP53 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.