SCHEMBL3679372

SCHEMBL3679372

O=C(Nc1ccc(Br)cc1)c1ccc(Br)cc1

nearest known ligand 0.76

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.76
MEN1 O00255 5/20 0.76
TP53 P04637 3/20 0.71
POLB P06746 2/20 0.67
USP2 O75604 1/20 0.67
MAPT P10636 4/20 0.64
RAB9A P51151 3/20 0.63
NPC1 O15118 2/20 0.63
LMNA P02545 1/20 0.63
PKM P14618 1/20 0.63
APEX1 P27695 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
KDM4E B2RXH2 1/20 0.63
MAPK1 P28482 1/20 0.62
CYP11B1 P15538 1/20 0.61
CYP11B2 P19099 1/20 0.61
SAE1 Q9UBE0 1/20 0.60
UBA2 Q9UBT2 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21798720 1.00 KMT2A (0.76) KMT2AMEN1TP53POLBUSP2
SCHEMBL674688 0.94 HDAC6 (0.69) KMT2AMEN1TP53POLBUSP2
SCHEMBL16592202 0.92 KMT2A (0.74) KMT2AMEN1TP53POLBUSP2
SCHEMBL16583981 0.92 KMT2A (0.74) KMT2AMEN1TP53POLBUSP2
SCHEMBL2461226 0.92 MAPT (0.71) KMT2AMEN1TP53POLBUSP2
SCHEMBL24426120 0.90 KMT2A (0.65) KMT2AMEN1TP53POLBUSP2
SCHEMBL1753199 0.90 RAB9A (0.81) KMT2AMEN1TP53POLBUSP2
SCHEMBL7019006 0.90 PTPN1 (0.73) KMT2AMEN1TP53POLBMAPT
SCHEMBL16589405 0.90 KMT2A (0.65) KMT2AMEN1TP53POLBUSP2
SCHEMBL1724745 0.90 KMT2A (0.65) KMT2AMEN1TP53POLBUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118420484-B Method for preparing amide compounds 四川大学 2024-08-30 CN disclosed
CN-118420484-A Method for preparing amide compounds 四川大学 2024-08-02 CN disclosed
WO-2022192162-A1 NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) 2022-09-15 WO disclosed
WO-2022192162-A1 NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) 2022-09-15 WO disclosed
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 EP disclosed
US-6933068-B2 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2005-08-23 US disclosed
EP-1245554-B1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR CORP (JP) 2005-01-26 EP disclosed
US-6833426-B2 A proton-conductive membrane containing the sulfonic acid group-containing polyarylene (co)polymer JSR CORPORATION (JP) 2004-12-21 US disclosed
US-6794480-B2 POLYARYLENE-BASED COPOLYMER USEFUL AS PROTON-CONDUCTIVE MEMBRANE WHICH CAN BE USED AS ELECTRON FOR PRIMARY BATTERY, ELECTROLYTE FOR SECONDARY BATTERY, HIGH MOLECULAR SOLID ELECTROLYTE FOR FUEL CELL JSR CORPORATION (JP) 2004-09-21 US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
US-20020177656-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR CORPORATION (JP) 2002-11-28 US disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed
EP-1245554-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR Corporation (JP) 2002-10-02 EP disclosed