Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.34 |
| ▸ | DPP4 | P27487 | 17/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.32 |
| ▸ | FAP | Q12884 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21142893 | 0.88 | DPP4 (0.33) | DPP4 | |
| SCHEMBL21343591 | 0.85 | DPP4 (0.34) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL19528503 | 0.85 | DPP8 (0.36) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL15396012 | 0.84 | PIK3CD (0.42) | DPP8DPP7DPP4DPP9 | |
| SCHEMBL19657875 | 0.83 | — | — | |
| SCHEMBL19527989 | 0.81 | PIK3CD (0.30) | — | |
| SCHEMBL19772721 | 0.78 | — | — | |
| SCHEMBL21897066 | 0.75 | PEPD (0.35) | — | |
| SCHEMBL21343612 | 0.74 | — | — | |
| SCHEMBL18994153 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342085-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342085-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, SARS1 | DPP8 113/4885DPP7 246/4885DPP4 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.