Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17776400 | 1.00 | TSHR (0.52) | TSHR | |
| SCHEMBL17776413 | 0.82 | MEN1 (0.35) | TSHR | |
| SCHEMBL17776281 | 0.82 | MEN1 (0.35) | TSHR | |
| SCHEMBL19316994 | 0.81 | TSHR (0.70) | TSHR | |
| SCHEMBL21049840 | 0.81 | TSHR (0.70) | TSHR | |
| SCHEMBL31618958 | 0.81 | TSHR (0.70) | TSHR | |
| SCHEMBL932686 | 0.81 | TSHR (0.70) | TSHR | |
| SCHEMBL21049848 | 0.81 | TSHR (0.70) | TSHR | |
| SCHEMBL12092183 | 0.81 | TSHR (0.70) | TSHR | |
| SCHEMBL12505785 | 0.81 | TSHR (0.70) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205309-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-11-30 | — | — | WO | disclosed |