Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CKS1B | P61024 | 1/20 | 0.52 |
| ▸ | SKP1 | P63208 | 1/20 | 0.52 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.52 |
| ▸ | SMO | Q99835 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056570 | 0.85 | KDM4E (0.63) | MEN1KMT2AKDM4ECYP2C19ALDH1A1 | |
| SCHEMBL19658643 | 0.84 | CKS1B (0.50) | MEN1KMT2AKDM4ECKS1BSKP1 | |
| SCHEMBL19658647 | 0.84 | KDM4E (0.70) | MEN1KMT2AKDM4ECKS1BSKP1 | |
| SCHEMBL19652277 | 0.83 | MEN1 (0.55) | MEN1KMT2AKDM4ECYP2C19ALDH1A1 | |
| SCHEMBL19652097 | 0.83 | MEN1 (0.55) | MEN1KMT2AKDM4ECYP2C19CKS1B | |
| SCHEMBL19658659 | 0.83 | CKS1B (0.49) | MEN1KMT2ACKS1BSKP1SKP2 | |
| SCHEMBL2301058 | 0.82 | CKS1B (0.60) | KDM4ECYP2C19CKS1BSKP1SKP2 | |
| SCHEMBL28982919 | 0.80 | ACACB (0.48) | MEN1KMT2AKDM4ECKS1BSKP1 | |
| SCHEMBL4954279 | 0.80 | GPR119 (0.61) | MEN1KMT2AKDM4ECYP2C19CKS1B | |
| SCHEMBL19658656 | 0.80 | LRRK2 (0.50) | CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170340604-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170340604-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | BRD4, BRDT, BRD3 | MEN1 1364/4885KMT2A 165/4885KDM4E 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.