Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19658464 | 0.94 | ACHE (0.52) | ACHEBCHEDPP4PREPFAP | |
| SCHEMBL19652123 | 0.85 | ACHE (0.41) | ACHEBCHECHRM4 | |
| SCHEMBL19658462 | 0.83 | ACHE (0.38) | ACHEBCHEDPP4PREPFAP | |
| SCHEMBL19658737 | 0.83 | ACHE (0.57) | ACHEDPP4PREPFAP | |
| SCHEMBL791906 | 0.81 | ACHE (0.56) | ACHE | |
| SCHEMBL19658593 | 0.80 | ACHE (0.62) | ACHE | |
| SCHEMBL19652281 | 0.80 | ACHE (0.39) | ACHEBCHE | |
| SCHEMBL19658759 | 0.79 | ACHE (0.53) | ACHECHRM4 | |
| SCHEMBL19658743 | 0.77 | HRH3 (0.40) | ACHEBCHEDPP4PREPFAP | |
| SCHEMBL19658780 | 0.77 | HRH3 (0.37) | ACHEBCHEDPP4PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170340604-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170340604-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | BRD4, BRDT, BRD3 | ACHE 2649/4885BCHE 1184/4885DPP4 3303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.